There is some drawback. The main one : app can’t communicate with each other.
Example firefox and his extension keepass. As keepass can’t communicate with firefox, you have to open both apps and switch their windows.
You can use flatseal to manage communication between apps but that’s not an easy process and may prove a security issue if you don’t understand the technical jargon.
That’s an interesting case.
Yes, anyone can check vote on lemvotes.org and i apologize for this lousy message. In this case, you mass downvoted several posts in a row.